Both boards share the same AM5 socket, making them compatible with the same range of AMD processors, and both offer a solid feature set for their tier: dual BIOS, easy BIOS reset, RGB lighting, overclocking support, a 3-year warranty, and HDMI 2.1 output. Neither board includes integrated graphics or a built-in CPU, so a discrete GPU or a processor with onboard graphics is required in both cases. For most buyers, these shared fundamentals mean the platform experience is essentially identical at the CPU and display-output level.
The most meaningful split between these two boards comes down to form factor and wireless connectivity. The Prime B840-Plus WiFi is a full ATX board (305 × 244 mm), while the Prime B840M-A is a Micro-ATX (244 × 244 mm). In practice, the smaller footprint of the Micro-ATX makes it better suited to compact or mid-tower builds with limited interior space, whereas the ATX variant gives builders more room for expansion slots and potentially better component spacing for airflow and cable management. Critically, the B840-Plus WiFi includes built-in Wi-Fi and Bluetooth, while the B840M-A offers neither — meaning users of the Micro-ATX board who need wireless connectivity must add a PCIe or USB adapter, which adds cost and occupies an expansion slot.
The Prime B840-Plus WiFi holds a clear advantage in this group. Its integrated wireless stack is a genuinely significant real-world benefit — eliminating the need for extra hardware and keeping the build cleaner — while its ATX size only matters if your case and use case call for a larger board. The B840M-A makes sense primarily for those who are certain they will use a wired network and need a smaller board; otherwise, the B840-Plus WiFi delivers more value out of the box.