At the core, both the Asus Prime RTX 5060 OC and the Gainward RTX 5060 Ghost OC share the same foundation: identical 2280 MHz base clock, 3840 shading units, 120 TMUs, 48 ROPs, and 1750 MHz memory speed. This means the two cards are built on the exact same GPU die with the same memory subsystem, and any performance differences will come entirely from how aggressively each manufacturer has tuned the boost behavior.
The one meaningful differentiator here is the GPU turbo clock: the Asus Prime OC reaches 2565 MHz versus the Gainward Ghost OC's 2535 MHz — a 30 MHz gap. This translates directly into slightly higher throughput across every compute metric: the Asus edges ahead with 19.7 TFLOPS of floating-point performance versus 19.47 TFLOPS, a 123.1 GPixel/s pixel fill rate versus 121.7 GPixel/s, and a texture rate of 307.8 GTexels/s versus 304.2 GTexels/s. In practice, a ~1.2% clock advantage is unlikely to produce a perceptible difference in frame rates or rendering workloads under real-world conditions.
Both cards support Double Precision Floating Point (DPFP), which matters for compute-heavy or scientific workloads beyond typical gaming. Overall, the Asus Prime RTX 5060 OC holds a narrow but measurable performance edge on paper due to its higher boost clock. However, the gap is so slim that thermal behavior, power delivery, and driver variance in real use could easily close or even reverse it. For pure gaming, these two cards are effectively performance-equivalent.