The Asus TUF Gaming B650E-E Wi-Fi and Gigabyte B550M DS3H AC R2 both offer solid general features, but there are key differences. The Asus TUF Gaming B650E-E Wi-Fi has an AM5 CPU socket, while the Gigabyte B550M DS3H AC R2 uses an AM4 socket. The chipset on the Asus board is B650, whereas the Gigabyte board uses B550, which indicates a slight generation gap. Both motherboards are Wi-Fi enabled, but the Asus board supports a wider range of Wi-Fi versions: Wi-Fi 4, Wi-Fi 5, Wi-Fi 6, and Wi-Fi 6E, compared to the Gigabyte board which supports Wi-Fi 4 and Wi-Fi 5 only.
Both motherboards have Bluetooth functionality, with the Asus TUF Gaming B650E-E supporting Bluetooth 5.3 and the Gigabyte B550M DS3H AC R2 supporting Bluetooth 5. This is a small difference in Bluetooth versions. Both motherboards feature HDMI 2.1 ports, making them suitable for high-definition video output. In terms of overclocking, both are easy to overclock, and neither has dual BIOS or an easy BIOS reset feature. RGB lighting is included in both products.
Regarding physical dimensions, the Asus board has a larger form factor at 244 mm by 305 mm (ATX), while the Gigabyte board is more compact at 244 mm by 244 mm (Micro-ATX). The warranty period is the same for both, offering 3 years of coverage. Neither board includes integrated graphics or an integrated CPU, and both have a single CPU socket. The Asus TUF Gaming B650E-E Wi-Fi also supports the latest Bluetooth aptX standard, which is absent from the Gigabyte model.