At a foundational level, these two earbuds are well-matched: both use USB-C, share a 10 m Bluetooth range, support AAC, and skip NFC pairing. The more meaningful distinctions lie in Bluetooth version, codec support, and pairing convenience. The OnePlus Buds 4 runs on Bluetooth 5.4 versus the Bose's 5.3 — a minor generational step that brings incremental improvements in connection stability and efficiency, though the real-world difference for most users will be negligible.
The codec split is where the two earbuds diverge in a more ecosystem-dependent way. The Bose QuietComfort Ultra Earbuds (2nd Gen) supports aptX Adaptive, Qualcomm's flagship codec that dynamically adjusts bitrate for high-resolution, low-latency audio — particularly valuable for Android users on compatible Qualcomm-powered devices. The OnePlus Buds 4 counters with LDHC, a high-resolution codec capable of very high bitrates, but one with a narrower device compatibility footprint. Neither supports LDAC, so Sony-ecosystem users are equally unserved by both. The OnePlus Buds 4 also adds fast pairing, which streamlines the initial setup process on supported devices — a small but genuinely appreciated convenience the Bose omits.
This category is close, but the edge shifts depending on your device. For users with Qualcomm-based Android phones, the Bose's aptX Adaptive is the more universally recognized high-quality codec. For OnePlus device owners or those with LDHC-compatible sources, the OnePlus Buds 4 is the stronger fit — and its fast pairing support adds a tangible convenience bonus. On purely objective connectivity breadth, the two are evenly matched with a slight practical nod to the Bose for aptX Adaptive's wider compatibility.