Connectivity is where these two headphones finally diverge in a meaningful way. Both support wireless and wired use, share an identical 10 m Bluetooth range, and neither offers NFC pairing — so far, so equal. The real story is in codec support. The Bose QuietComfort Ultra (2nd Gen) ships with aptX Adaptive as its sole high-quality wireless codec, while the Bowers & Wilkins Px7 S3 supports aptX Adaptive, aptX, aptX HD, aptX Lossless, and LDAC — a dramatically broader suite.
That codec breadth matters in practice. LDAC, developed by Sony, is widely supported on Android devices and capable of streaming at up to 990 kbps, making it a go-to for high-res audio listeners. aptX HD and aptX Lossless extend compatibility further across a range of source devices. The Px7 S3's wider codec roster means it can negotiate a higher-quality connection with more source devices out of the box, without falling back to compressed SBC. The Bose, by contrast, is fully dependent on the source device also supporting aptX Adaptive — a newer standard that, while excellent when available, is not yet as universally implemented.
On the Bluetooth version, the Bose carries a slight edge with Bluetooth 5.4 versus the Px7 S3's 5.3, but the practical difference between these two sequential versions is negligible for most users. Edge: Bowers & Wilkins Px7 S3. Its significantly richer codec support gives it far greater compatibility with high-resolution audio sources, making it the stronger choice for listeners who prioritize wireless audio quality across a variety of devices.