The Canon EOS R6 Mark III and Panasonic Lumix DC-S1 II both feature full-frame sensors, with the Canon utilizing the Canon RF lens mount and the Panasonic using the Leica L lens mount. In terms of autofocus, the Canon offers 1053 focus points, significantly more than the Panasonic's 779. Both cameras feature phase-detection autofocus and AF tracking for photos, ensuring fast and precise focusing.
On the imaging front, the Canon boasts a 32.5 MP main camera, providing higher resolution compared to the Panasonic's 24.1 MP. The Canon's maximum ISO is 64000, expandable to 102400, while the Panasonic reaches a maximum of 51200, expandable to 204800. Both cameras offer sensor shift stabilization, with the Canon achieving 8.5 stops of stabilization and the Panasonic providing 8 stops. The Canon's continuous shooting speed is 12 fps (mechanical), whereas the Panasonic can shoot at 10 fps (mechanical).
Both cameras have similar features, such as manual focus, touch autofocus, manual shutter speed, and a CMOS sensor. They also share a flash sync speed of 0.004 s, a two-stage shutter, serial shot mode, and manual exposure. The Canon offers a maximum exposure time of 30 s, while the Panasonic allows for a longer exposure of up to 60 s. Both cameras have maximum electronic shutter speeds of 6.25E-5 s. The Canon lacks a stacked CMOS sensor, which the Panasonic includes. Finally, both cameras allow for combining image stabilization for even smoother footage.