The Canon EOS R6 Mark III and Panasonic Lumix DC-S1 IIE are both mirrorless cameras, each equipped with an electronic viewfinder (EVF) offering 100% viewfinder coverage. While the Canon model features a 1600k dot screen resolution, the Panasonic's screen resolution is slightly higher at 1840k dots. Both cameras have flip-out screens, but the Canon has a 3″ screen, while the Panasonic offers a slightly larger 3.2″ display. Both cameras are weather-sealed (splashproof), though the Canon operates in a temperature range from 0°C to 40°C, whereas the Panasonic has a broader operating temperature range from -10°C to 40°C.
In terms of physical dimensions, the Canon EOS R6 Mark III is a bit more compact with a width of 138.4 mm, height of 98.4 mm, and thickness of 88.4 mm, weighing 699 g. On the other hand, the Panasonic Lumix DC-S1 IIE is slightly larger and heavier, measuring 134.3 mm in width, 102.3 mm in height, 91.8 mm in thickness, and weighing 795 g. The Canon has a volume of 1203.9 cm³, while the Panasonic has a slightly larger volume at 1261.2 cm³.
Both cameras are system cameras and support a hot shoe, but neither has a built-in flash. Additionally, neither model has a tilting viewfinder. The Canon model has a touchscreen and is rated for operating in temperatures as low as 0°C, while the Panasonic offers a wider operating temperature range down to -10°C and also includes a touchscreen. Both cameras share the same maximum operating temperature of 40°C.