At their core, the FiiO M21 and HiBy R6 III are built on a remarkably similar foundation: both pack the same Cirrus Logic CS43198 x4 DAC configuration, identical 64GB internal storage, 4GB of RAM, and offer the same trio of audio outputs (3.5 mm, 4.4 mm, and USB-C). Their format support is functionally equivalent as well, covering all major lossless and lossy codecs including DSD and MQA. For a buyer focused purely on audio hardware parity, these two devices start from nearly the same place.
The differences emerge in the platform and endurance specs. The M21 runs on a Snapdragon 680 paired with Android 13, while the R6 III uses the older Snapdragon 665 on Android 12. In practice, the 680 is a more modern, efficient chip, which likely contributes to the M21's superior real-world stamina: 15 hours of battery life versus 13 hours on the R6 III — a meaningful gap for long listening sessions or travel days. The M21 also recharges faster, needing just 1.5 hours compared to the R6 III's 2 hours. The R6 III does edge ahead on SNR at 126 dB versus the M21's 124 dB, a 2 dB difference that is technically measurable but unlikely to be audible in real-world use.
Overall, the FiiO M21 holds a clear practical advantage in this group: a newer chipset, a more current Android version, longer battery life, and faster charging all tip the scales in its favor. The R6 III's marginal SNR lead does not meaningfully offset these platform-level advantages for most users.