Both boards share the same fundamental platform: the AM5 socket with a B840 chipset in a Micro-ATX form factor, with nearly identical dimensions (a negligible 0.2 mm difference). They support overclocking, include Bluetooth 5.3, output via HDMI 2.1, and carry a 3-year warranty — so for the core build essentials, there is no practical difference to weigh.
The meaningful divergences lie in three areas. First, wireless connectivity: the MSI B840M Gaming Plus supports Wi-Fi 6E (802.11ax on 6 GHz), while the Gigabyte B840M DS3H tops out at Wi-Fi 6. In real-world terms, Wi-Fi 6E access to the uncongested 6 GHz band can deliver lower latency and faster sustained speeds in dense environments — a genuine advantage if your router supports it. Second, BIOS resilience takes opposite approaches: the Gigabyte offers dual BIOS (a hardware-level failsafe if a flash goes wrong), whereas the MSI provides an easy BIOS reset mechanism (faster recovery from a bad configuration). These cater to different risk profiles. Third, the MSI includes RGB lighting while the Gigabyte does not — relevant only for aesthetics.
Overall, the MSI B840M Gaming Plus Wi-Fi6E holds a clearer edge in this group, primarily due to its superior Wi-Fi 6E support and easier BIOS recovery — features with tangible practical upside. The Gigabyte's dual BIOS is a legitimate counter-advantage for users who flash firmware frequently and want a hardware safety net, but for most builders the MSI's wireless future-proofing tips the balance.