Port selection is where these two boards diverge most visibly, and the differences reflect genuinely different design philosophies. The Gigabyte B850 Gaming X WiFi6E leans toward legacy-friendly breadth: it offers three USB 3.2 Gen 1 Type-A ports alongside one Gen 2 Type-A, giving it a stronger total count of high-speed USB-A connections — practical for users with mice, keyboards, headsets, and hubs that still rely on the standard Type-A form factor. It also includes a PS/2 port, a niche but occasionally valued feature for enthusiasts using older input devices or those who need interrupt-driven input during BIOS operations.
The MSI B850 Gaming Plus WiFi makes a different trade-off, cutting back to just one USB 3.2 Gen 1 Type-A port but doubling the modern USB-C presence to two Gen 2 Type-C ports. That second USB-C connector is increasingly useful as peripherals, external drives, and displays shift toward the format. More notably, the Gigabyte includes an HDMI output on the rear I/O while the MSI does not — a meaningful distinction for users who want a secondary display connection option alongside the shared single DisplayPort output.
Neither board includes USB4 or Thunderbolt, so both sit at the same high-end ceiling. On balance, the Gigabyte holds a modest edge here: the additional USB-A ports reduce the need for hubs in typical desktop setups, and the HDMI output adds a display flexibility that the MSI simply lacks. The MSI's dual USB-C is a genuine plus for modern workflows, but it does not fully offset the overall connectivity advantage the Gigabyte offers.