Across most feature checkboxes, these two cards are remarkably aligned — both support ray tracing, DLSS, 3D output, multi-display configurations up to 4 screens, Intel Resizable BAR, and identical OpenGL 4.6 and OpenCL 3 API versions. For the vast majority of supported software, users of either card will have access to the same feature set.
The one technically meaningful distinction is the DirectX version: the 5060 Ti Gaming OC lists DirectX 12 Ultimate, while the RTX Pro 5000 Blackwell lists DirectX 12. In practice, DirectX 12 Ultimate is a certification tier built on top of DX12 that formalizes support for hardware ray tracing, variable rate shading, mesh shaders, and sampler feedback under a unified label. Whether this difference has any practical impact depends entirely on the software being run — titles or tools explicitly targeting DX12 Ultimate features may expose this gap, though many applications do not distinguish between the two at this level. The other differentiator, RGB lighting on the 5060 Ti, is purely aesthetic and carries no functional significance for performance or compatibility.
On balance, this group is essentially a near-tie with a narrow edge to the 5060 Ti Gaming OC on paper, solely due to the DirectX 12 Ultimate designation. However, users buying the RTX Pro 5000 are overwhelmingly targeting professional workloads where this specific certification is rarely a deciding factor. For gaming-oriented feature completeness, the 5060 Ti holds a slight advantage; for professional use cases, the distinction is largely irrelevant.