The core count gap between these two processors is enormous. The Xeon 6781P brings 80 cores and 160 threads to the table, versus the 6516P-B's 20 cores and 40 threads — a 4x advantage in parallelism. For workloads that scale horizontally, such as large-scale virtualization, containerized cloud environments, or massively parallel data processing, the 6781P can handle dramatically more simultaneous tasks without requiring additional sockets or servers.
On a per-core frequency basis, the two chips are closely matched. Both share similar base clocks — 2.3 GHz for the 6516P-B versus 2.0 GHz for the 6781P — and turbo peaks of 3.5 GHz and 3.8 GHz respectively, with neither holding an unlocked multiplier. This means single-threaded responsiveness is broadly comparable, with the 6781P even edging ahead slightly at peak boost. For lightly-threaded applications, neither processor offers a decisive frequency advantage.
Cache tells a similar story of scale. The 6781P's 336 MB L3 cache dwarfs the 6516P-B's 80 MB, which translates to far fewer costly memory fetches in data-intensive workloads like in-memory databases or large working-set analytics. Per-core cache ratios are nearly identical (4 MB/core L3 for the 6516P-B versus 4.2 MB/core for the 6781P), confirming the 6781P's advantage is one of scale, not architectural superiority per core. Overall, the 6781P holds a commanding performance edge for throughput-oriented, multi-threaded workloads, while the 6516P-B remains a capable option where core count demands are more modest.