Both processors field the same 32 cores and 64 threads, and both use Turbo Boost 2 with a locked multiplier — so the competitive ground here is defined entirely by clock speeds and cache, where the differences are substantial. The Xeon 6745P starts at a base clock of 3.1 GHz versus the 6546P-B's 2.3 GHz, and that 800 MHz gap carries through to boost as well: the 6745P peaks at 4.3 GHz while the 6546P-B tops out at 3.5 GHz. For single-threaded or lightly-threaded workloads — database queries, ERP transactions, latency-sensitive applications — higher clock speeds translate directly to faster response times, and the 6745P holds a meaningful lead across the entire frequency range.
The cache gap is even more striking. The 6745P carries 336 MB of L3 cache at 10.5 MB per core, compared to the 6546P-B's 128 MB at 4 MB per core — a 2.6× advantage in total cache capacity. In practice, a larger L3 cache reduces how often the processor must reach out to slower main memory, which is especially impactful for in-memory analytics, large dataset processing, and high-throughput virtualization workloads where cache misses are a primary bottleneck.
Across every performance dimension in this group, the Xeon 6745P has a clear and decisive advantage: higher base and turbo clocks, and dramatically more cache per core. The 6546P-B's lower clock speeds and smaller cache make it the slower option for compute-intensive tasks, though its lower TDP — established in the General Info group — is the trade-off that makes it viable where power efficiency matters more than peak throughput.