Both the MSI B850 Gaming Plus WiFi and the MSI Pro B850M-P Wi-Fi share the same AM5 socket and B850 chipset, meaning they target the same generation of AMD processors with identical platform capabilities. They also match on wireless connectivity — both support Wi-Fi 7 and Bluetooth 5.4 — and share the same feature checklist: RGB lighting, dual BIOS, easy BIOS reset, and overclocking support. Neither board includes integrated graphics or an integrated CPU, which is standard for this class.
The single most meaningful differentiator in this group is form factor. The Gaming Plus WiFi is a full-size ATX board (304.8 × 243.8 mm), while the Pro B850M-P Wi-Fi is a Micro-ATX design (243.8 × 243.8 mm). The ATX format gives the Gaming Plus WiFi more physical real estate, which typically translates to more expansion slots, better component spacing, and greater cooling headroom — though those details fall outside this spec group. The Micro-ATX Pro B850M-P Wi-Fi, being square and more compact, is better suited to smaller cases and space-constrained builds.
For this general info group, the two boards are essentially tied on features and platform support. The deciding factor here is purely physical: if you are building in a standard mid-tower and want maximum expandability potential, the Gaming Plus WiFi has the edge by virtue of its larger ATX footprint. If your build demands a smaller chassis, the Pro B850M-P Wi-Fi is the logical choice without sacrificing any of the core feature parity.