The Fujifilm X100VI is a compact, non-system camera measuring 128 × 74.8 × 55.3 mm and weighing 521 g, built with a weather-sealed body rated for use between 0 °C and 40 °C. It features a hybrid viewfinder system combining an electronic viewfinder at 3690k dots resolution and an optical viewfinder, both offering 100% coverage, though the viewfinder does not tilt. The rear 3-inch touchscreen delivers 1620k dots of resolution and supports a flip-out mechanism for flexible shooting angles. A built-in flash and hot shoe are both present, while a lens hood is not included. The camera is not a system camera, meaning it does not support interchangeable lenses.
The camera uses a 40.2 MP APS-C CMOS sensor — not a stacked variant — with a fixed 23 mm lens that opens to f/2 at its widest and stops down to f/16, fitted with 9 rounded aperture blades and capable of focusing as close as 0.1 m as well as to infinity. Sensor-shift stabilization provides up to 6 stops of compensation per CIPA standards, though there is no separate optical image stabilization system. The autofocus system offers 425 focus points with AF tracking, touch autofocus, and full-time manual focus override, while manual focus, manual shutter speed, manual ISO, and manual white balance are all supported. Native ISO reaches 12800, expandable to 51200, and exposure times extend to 30 s on the long end, with a mechanical shutter topping out at 1/4000 s and the electronic shutter reaching approximately 1/180,000 s. Continuous mechanical shooting is available at 11 fps in burst mode, and the camera also supports in-camera panorama creation, a built-in HDR mode, and a two-stage shutter release.
The Fujifilm X100VI records video at 3150-wide resolution up to 30 fps with a movie bitrate of 200 Mbps, and also supports a 24p cinema mode for a more filmic frame rate. Continuous autofocus remains active during recording, and a timelapse function is built in. Audio is handled by a dual-microphone stereo setup, and a dedicated microphone input allows for an external mic connection; however, there is no 3.5 mm headset jack for monitoring audio output.
The camera runs on a removable, rechargeable battery rated at 1260 mAh, with a CIPA-rated life of 450 shots per charge. A battery level indicator is on hand to keep the remaining charge visible during use.
Processing is handled by the X-Processor 5, and the camera supports both RAW capture and lossless compressed RAW. Wireless connectivity covers Wi-Fi 5 (802.11ac) and Wi-Fi 4 (802.11n) alongside Bluetooth 4.2, with smartphone remote control also supported; NFC and GPS are not included. For wired connections, the camera offers a USB Type-C port and an HDMI output. A single external memory slot is available, as the camera does not have dual card slots. The hot shoe is a standard type without advanced functionality, and pixel shift shooting is not supported.
The camera's USB interface operates at USB 3.2 speeds.